ENGCB527-19A (HAM)

Advanced Biological Engineering

15 Points

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Division of Health Engineering Computing & Science
School of Engineering

Staff

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Convenor(s)

Aydin Berenjian

Aydin Berenjian
5119
EF.3.02
To be advised
aydin.berenjian@waikato.ac.nz

Mark Lay

Mark Lay
4556
C.3.01
To be advised
mark.lay@waikato.ac.nz

Lecturer(s)

Administrator(s)

Placement Coordinator(s)

Tutor(s)

Student Representative(s)

Lab Technician(s)

Librarian(s)

: debby.dada@waikato.ac.nz

You can contact staff by:

  • Calling +64 7 838 4466 select option 1, then enter the extension.
  • Extensions starting with 4, 5, 9 or 3 can also be direct dialled:
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    • For extensions starting with 3: dial +64 7 2620 + the last 3 digits of the extension e.g. 3123 = +64 7 262 0123.
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Paper Description

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This 15-point paper will cover various aspects of biochemical engineering used in producing biologically derived products, such as upstream processing including media preparation and sterilisation for fermentors; microbial growth; bioreactor design, monitoring, control, modelling and optimisation; downstream processing including filtration, centrifugation and protein separations using chromatography. The chromatography part of the course will cover theory, column dispersion, optimisation, large scale and continuous chromatography, and a practical component in the lab where students will get the opportunity to separate proteins using chromatography equipment on the basis of protein size, charge and hydrophobicity. Principles behind meat processing, meat aging and quality, and food processing and preservation will be covered. Students will also be introduced to Superpro Designer, process simulation software used in biochemical engineering.

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Paper Structure

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Lectures/Tutorials

There are three lectures per week.

Computer Labs

There will be lectures and tutorials on SuperPro Designer. Location and timing will be advised during the course.

Laboratory/Project Work

Three to four 2-3 hour laboratories on protein separation using the AKTA FPLC will be scheduled in the first half of A semester. These will be held in E.G.01.

International Students

For international students in New Zealand under student visas, regular attendance is part of your visa obligation and is checked as a requirement on the University under the Code of Practice for the Pastoral Care of International Students, to which the University is a signatory. Academic staff are formally required to monitor attendance in classes and submission of compulsory assessment events/items and to report to Waikato International in the event that any problem with irregular attendance or non-submission is not resolved.

Admission

Normally only students in the Chemical and Biological Engineering programme of the BE(Hons) are admitted. Students are expected to have completed Year 3 of their programme.
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Learning Outcomes

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Students who successfully complete the course should be able to:

  • Develop strategies to purify products, particularly proteins.
    Linked to the following assessments:
    • Test 1 (1)
    • Test 2 (2)
    • SuperPro assignment (3)
    • Research paper & presentation (4)
    • Protein separation assignment (5)
  • Use SuperPro Designer to model bioprocesses.
    Linked to the following assessments:
    • SuperPro assignment (3)
  • Calculate sterilisation time.
    Linked to the following assessments:
    • Test 1 (1)
    • Research paper & presentation (4)
  • Develop a medium for growing microorganisms and other cells.
    Linked to the following assessments:
    • Test 1 (1)
    • Test 2 (2)
    • Research paper & presentation (4)
  • Determine kinetic parameters, yield coefficients and productivity of biological processes, and identify factors that optimize growth and product formation.
    Linked to the following assessments:
    • Test 1 (1)
    • Test 2 (2)
    • Research paper & presentation (4)
  • Understand the biochemical reactions in a major New Zealand food processing industry, namely meat and meat byproduct processing.
    Linked to the following assessments:
    • Test 1 (1)
    • Test 2 (2)
    • Research paper & presentation (4)
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Assessment

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Final Examination

The 3-hour final exam will cover all material in the course including lectures, any field visits, lectures by visitors, project work, and seminar presentations. Format of the final examination will be discussed in lectures at the end of the course.

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Assessment Components

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The internal assessment/exam ratio (as stated in the University Calendar) is 50:50. There is no final exam. The final exam makes up 50% of the overall mark.

The internal assessment/exam ratio (as stated in the University Calendar) is 50:50 or 0:0, whichever is more favourable for the student. The final exam makes up either 50% or 0% of the overall mark.

Component DescriptionDue Date TimePercentage of overall markSubmission MethodCompulsory
1. Test 1
10 Apr 2019
9:00 AM
10
2. Test 2
29 May 2019
9:00 AM
10
3. SuperPro assignment
18 Mar 2019
5:00 PM
7.5
  • Online: Submit through Moodle
4. Research paper & presentation
29 Apr 2019
5:00 PM
15
  • In Class: In Workshop
  • Online: Submit through Moodle
5. Protein separation assignment
24 May 2019
5:00 PM
7.5
  • Online: Submit through Moodle
6. Exam
50
✔
Assessment Total:     100    
Failing to complete a compulsory assessment component of a paper will result in an IC grade
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Required and Recommended Readings

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Recommended Readings

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Pauline M Doran (2013) Bioprocess Engineering Principles2nd edn, Academic Press: London (TP248.3.D67 2013)

James E Bailey & David F Ollis (1977) Biochemical Engineering Fundamentals2nd edn, McGraw Hill: New York (TP248.3.B34 1977)

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Online Support

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This paper has a Moodle page (http://elearn.waikato.ac.nz) where class notices, assignments, lecture notes and readings will be given (unless handed out in class).

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Workload

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Up to six contact hours per week. Students are expected to spend 10-12 hours per week reading, assignments and independent study.

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Linkages to Other Papers

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Prerequisite(s)

Prerequisites: ENGCB322 or ENMP322

Corequisite(s)

Equivalent(s)

Restriction(s)

Restricted papers: ENMP427

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